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In histology, bodies are broadly classified into the following categories: 1. Naturally occurring body - a mass of matter found anatomically or physiologically in organs and tissues 2. Foreign body - a mass or entity that has been introduced from an external source. In other words, any mass found in an organ or tissue in which it does not normally belong
Lichen planus may occur on mucosal surfaces such as the oral mucosa or genitalia. Results: There were 34 females (68%) and 16 males. The mean age at diagnosis was 47.8 years for females and 61.7 years for males. Histological examination revealed an atrophic (62%), flattened (84%) epidermis with hyperkeratosis (92%) and occasional follicular plugging (34%). Poikiloderma of Civatte is characterised by confluent reddish-brown patches with atrophy that symmetrically involve sun-exposed areas such as the sides of the neck and lateral aspect of the cheeks.
Image. Histopathology Image 3 - Path Quiz Case -35 (Pathology Quiz Online) Dr Sampurna Roy. Medicine. Cases. Medical.
Poikiloderma of Civatte is a benign, common and chronic condition, which belongs to the group of melanodermas (pigmented skin disorders). The term 'poikiloderma' refers to a skin change with atrophy where hypopigmentation / hyperpigmentation changes and dilation of the fine blood vessels (telangiectasia) can be seen in the affected skin.
‘ Hyaline bodies’ are equivalent but occur in connective tissue. The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal junction by inflammatory cells. Secondary changes of the epidermis and papillary dermis along with type, distribution and density of inflammatory cells are used for the differential diagnoses of the various diseases that exhibit interface changes. Focal hypergranulosis and focal parakeratosis is present.
Jun 6, 2007 found in various sites of the body, includ- ing on the skin and in the Periodontology. “This comprehensive review outlines the situations an oral and maxillofacial pathology keratinocytes termed colloid or Civa
Nov 10, 2020 Which histologic feature of lichenoid drug eruption is absent in classic lichen planus?
lichenoid interface dermatitis pathology pathology in outline format with mouse over Civatte bodies. making the practice of pathology easier, better, and
These results indicate that K17 is a sensitive immunohistochemical marker for Civatte bodies and useful for differential diagnosis of oral lichen planus from other oral mucosal lesions. Civatte bodies are generated from denucleation of K17+ epithelial cells during the process of cell death via dyskeratosis, which is possibly related to blood capillary collapse.
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Keratin 17-positive Civatte bodies in oral lichen planus—distribution Division of Molecular and Diagnostic Pathology, while type C bodies did not always have a smooth outline, Eosinophilic apoptotic (necrotic) keratinocytes in the lower epidermis and at the dermoepidermal junction are a feature of many interface dermatoses but are most reliably found in lichen planus. These structures are universally known as Civatte bodies.
Foremost, early LS and lichen planus can show significant overlap, well described by Fung and LeBoit in 1998, 20 who reported that a psoriasiform lichenoid pattern, basilar epidermotropism, loss of papillary dermal elastic fibers, basement membrane thickening, and epidermal atrophy favor LS, whereas Civatte bodies, wedge-shaped hypergranulosis, basal squamatization, and pointed rete ridges
Named Cells and Bodies in Oral Pathology - Part I: A Ready Reckoner Shankar Gouda Patil 1, Roopa S Rao,2 Sanketh Sharath3 2 morphology of cell & structures.
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Keratin 17-positive Civatte bodies in oral lichen planus—distribution Division of Molecular and Diagnostic Pathology, while type C bodies did not always have a smooth outline,
Accurate histological diagnosis, although it can sometimes be difficult to establish, is essential for clinical management. Knowledge of the microanatomy of the skin is important to recognise the variable histological patterns of inflammatory skin diseases. This article reviews the Civatte body Civatte body A Civatte body (named after the French dermatologist Achille Civatte, 1877–1956) [35] is a damaged basal keratinocyte that has undergone apoptosis , and consist largely of keratin intermediate filaments, and are almost invariably covered with immunoglobulins , mainly IgM. [36] Keratin 17-positive Civatte bodies in oral lichen planus—distribution Division of Molecular and Diagnostic Pathology, while type C bodies did not always have a smooth outline, Kamino bodies are eosinophilic globoids. Kamino bodies are commonly observed microscopically with the condition spitz nevi, a benign melanocytic nevus, a type of skin lesion, affecting the epidermis and dermis. See also. List of cutaneous conditions; References Pathological and non-pathological bodies is the 'must have' reference website for the biological, medical and biomedical sciences. The site comprises more than 250 bodies, most of which are related to disease processes.
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The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal junction by inflammatory cells. Secondary changes of the epidermis and papillary dermis along with type, distribution and density of inflammatory cells are used for the differential diagnoses of the various diseases that exhibit interface changes. Focal hypergranulosis and focal parakeratosis is present. Numerous Civatte bodies are identified.
See also. List of cutaneous conditions; References Pathological and non-pathological bodies is the 'must have' reference website for the biological, medical and biomedical sciences. The site comprises more than 250 bodies, most of which are related to disease processes.